Oral and sublingual immunotherapy for food allergy. 2014

Oral and sublingual immunotherapy for food allergy


IgE-mediated food allergy is a potentially life-threatening allergic disease with an increase in prevalence in developed countries over the past 15 years. Currently, there are no approved forms of therapy and the standard of care is dietary restriction and ready access to emergency medications, such as self-injectable epinephrine and antihistamines. Allergen-specific modalities of treatment currently being studied include oral immunotherapy (OIT) and sublingual immunotherapy (SLIT). Both forms demonstrate the ability to desensitize patients to a variety of specific food allergens and show great promise. However, more research is needed to evaluate the safety and efficacy of OIT and SLIT prior to routine use in clinical practice.

Keywords: Food allergy, Oral immunotherapy, Sublingual immunotherapy, Desensitization, Tolerance

LINK TO: Oral and sublingual immunotherapy for food allergy. World Allergy Organ J. 2014 Dec 8;7(1):35.


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