Dr. Paul F. Detjen

Detjen_Dr_PaulDr. Paul Detjen

American Board of Allergy and Immunology-Certified in Allergy & Immunology
American Board of Internal Medicine-Certified in Internal Medicine
IL State Medical License-Active through 2017
FL State Medical License-Active through 2018

Education & Training
McGaw Medical Center of Northwestern University–Residency, Internal Medicine
Michael Reese Hospital and Medical Center–Residency, Internal Medicine
Rush University Medical Center–Residency, Anatomic and Clinical Pathology
McGaw Medical Center of Northwestern University–Fellowship, Allergy and Immunology
Washington University School of Medicine in St. Louis
McGaw Medical Center of Northwestern University–Chief Residency, Internal Medicine
Williams College

Awards, Honors, & Recognition
Top Tier MD, the doctor’s doctors–
Regional Top Doctor-
Castle Connolly, 2014
Leadership in Chicago Asthma Care-
Asthma in Chicago – RHAMC Respiratory Health Association of Metropolitan Chicago, 2011
Evanston Northwestern Healthcare Merritt C. Bragdon Society 1998
Top Doctor-
US News and World Report
Teaching Allergist of the Year-
American Academy of Allergy Asthma and Immunology
Mariel C Furlong Award-
Food Allergy Network
Asthma Leadership in Chicago-RHAMA Respiratory Health Association of Metropolitan Chicago, 2011

Hospital Affiliations:
NorthShore University Health System–Evanston, IL
Lurie Children’s Hospital of Chicago–Chicago, IL
Northwestern Memorial Hospital–Chicago, IL

From Dr. Detjen, Feb 2016: “Youngest age as of now is generally five. If all goes perfectly, you’re up to 12 peanuts twice a day in 4 1/2 months. It often takes a little longer due to illnesses or travel. We will be starting egg milk and other foods in about two months.

Patient of Dr. Detjen: “Thrilled to hear this! Dr. Detjen has been our allergist for 11 years, and I cannot say enough good things about him. He is just wonderful, brilliant, has an amazing bedside manner, and we have complete trust in him. His entire staff is absolutely great as well. We are two weeks into OIT.


Please WELCOME Dr. Paul F Detjen to our groups and our Desensitization Directory of OIT Providers! Dr. Detjen has adopted Dr. Wasserman’s protocol for peanut desensitization and has started taking OIT patients. His lovely receptionist, Patricia, will happily direct you to the nurses for additional information and to set your consultation appointments. They are just getting started so please be patient and they are coordinating this new service into their daily allergy and asthma practice.

We THANK YOU Dr. Detjen for being a part of our OIT Network and look forward to growing with your practice and sharing all your successes!

Interview with Dr. Detjen

Q: What is OIT?
A: Oral Immunotherapy for foods is the process of slowly, incrementally, and orally administering to a food allergic patient, the food to which they are allergic – desensitizing them – and then maintaining that desensitized state for a long enough time to induce the immune system to develop long-term tolerance.

Q: Why did you start OIT?
A: Everyone is aware of the marked increase in food allergy in the past few decades. There are so many families out there for whom food allergy dramatically and negatively alters the family’s lifestyle, not to mention adding significant risk to the patient as they grow up and increasingly head out into the world. I have been looking for a safe and, most importantly, effective way to administer immunotherapy to improve the lives of my food allergic patients and their families. This process is life-changing for them.

Q: When did you start OIT in your office?
A: We researched food immunotherapy options for several years, then during the fall/winter of 2015-16 we attended a number of educational sessions in San Antonio and Los Angeles and then witnessing and learning protocol in Dallas. Our first patients began OIT in February 2016.

Q: For which allergens is OIT available?
A: We have been successful with peanuts, sesame, and milk. We will soon be addingOIT for egg followed by tree nuts and wheat.

Q: What is the cost of OIT? Does insurance cover it?
A: Most offices have initial charges of around $100-400 to cover the acquisition and provision of the liquid capsule products for OIT, depending on what the local compounding pharmacy charges the office per capsule.

Most insurance providers pay for the OIT procedures. These procedures are not new and have been used by allergists for many decades if not longer. The first description of successful food OIT (egg) was more than 100 years ago.

Q: How long do patients have to eat the daily maintenance OIT food until they become fully tolerant?
A: This is one of our most commonly asked questions! Unfortunately, we won’t know the answer until we follow thousands of patients for many years. It is likely, in my opinion, that after three years of maintenance, most patients will need to eat that food approximately once a week for the foreseeable future. For more FAQS from our practice, refer to our FAQ Document.

Q: Is it challenging to convince patients to consume the one thing they have so vigilantly avoided?
A: It has been so gratifying to see our patients and their families bravely address these weekly up doses, some of which are more difficult than others. Both the first capsule and the first peanut (or equivalent) have their own challenges. One-third of what we do is desensitize to the food allergen; one-third is changing the mindset of the child; and one-third is changing the mindset of the mom. The last one can be the most gratifying of all.

Q: What results have you seen from OIT?
A: We have been happy to learn that 80 to 90% of our patients sail through this process up to maintenance without difficulty or side effects! We are encouraged by the fact that most of the 10 to 20% with stomach aches or other side effects can be coached successfully through OIT if it is done more gradually over a 10-to-12-month period. The biggest challenge for our office and staff is the labor intensive provision of materials, and then the logistical access of our patients to the office for their weekly up doses.

Q: How does OIT in a private practice differ from clinical trials?
A: In general the clinical trial OIT is a lower dose than what private practice allergists mean when they say OIT.

Q: How many doctors currently offer OIT, and how can our users find them?
A: Approximately 60 to 70 allergists in the United States are now providing private practice (higher dose) OIT to food allergic patients. This website (OIT101.org) allows you to find the allergist nearest you.

Q: Final Thoughts?
A: The rate of use of EpiPen is greater in food allergic patients who are still trying to avoid the food, compared with our patients who are undergoing private practice OIT.


Dr. Paul F. Detjen
Kenilworth Medical Associates
534 Green Bay Rd., Kenilworth, Illinois, 60043
(847) 256-5505


OIT Details

Doctor Name: Dr. Detjen
State: Illinois
Allergen: Peanut, Tree nuts, Milk, Egg, Wheat, Soy, Sesame
Treats single/multi allergens at once: Both options
Offers SLIT for food allergens: Yes

Additional Features:

Articles in Our Research & Learn Center

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Map to Office(s)






Publications & Presentations

Ketotifen fumarate and olopatadine hydrochloride in the treatment of allergic conjunctivitis: a real-world comparison of efficacy and ocular comfort. Ganz, M., Koll, E., Gausche, J., Detjen, P., Orfan, N.; Adv Ther. 2003 Mar 01.
Atrial fibrillation associated with anaphylaxis during venom and pollen immunotherapy. Patel, S.C., Detjen, P.F.; Ann Allergy Asthma Immunol. 2002 Aug.
Malignant potentially fatal asthma: a management strategy. Detjen, P. F., Greenberger, P. A., Grammer, L. C., Patterson, R.; Allergy Proc. 1992 Jan 01.
Stevens-Johnson syndrome (SJS): effectiveness of corticosteroids in management and recurrent SJS. Patterson, R., Grammer, L. C., Greenberger, P. A., Lawrence, I. D., Zeiss, C. R., Detjen, P. F., Ganz, M. A., Miller, T. P., Orfan, N. A., Sonenthal, K. R.; Allergy Proc. 1992 Mar 01.
Herpes simplex virus associated with recurrent Stevens-Johnson syndrome. A management strategy. Detjen, P. F., Patterson, R., Noskin, G. A., Phair, J. P., Loyd, S. O.; Arch Intern Med. 1992 Jul.
Effectiveness of early therapy with corticosteroids in Stevens-Johnson syndrome: experience with 41 cases and a hypothesis regarding pathogenesis. Patterson, R., Miller, M., Kaplan, M., Doan, T., Brown, J., Detjen, P., Grammer, L. C., Greenberger, P. A., Hogan, M. B., Latall, J.; Ann Allergy. 1994 Jul.
Stinging insect allergy and venom immunotherapy. Detjen, P., Greenberger, P. A.; Allergy Proc. 1993 Mar 01.
Oral allergy syndrome or anaphylaxis? Detjen, P.; Ann Allergy Asthma Immunol. 1996 Sep.
Success of a comprehensive school-based asthma intervention on clinical markers and resource utilization for inner-city children with asthma in Chicago: the Mobile C.A… Patel, B., Sheridan, P., Detjen, P., Donnersberger, D., Gluck, E., Malamut, K., Whyte, S., Miller, A., Qing, H.; J Asthma. 2007 Mar.

Journal Articles

Success of a Comprehensive School-Based Asthma Intervention on Clinical Markers and Resource Utilization for Inner-City Children with Asthma in Chicago: The Mobile CA…  Patel B, Sheridan P, Detjen PF, et al., J Asthma, 1/1/2007
Hymenoptera Allergy  Detjen, PF, Cutis, 1/1/2005
Ketotifen Fumarate and Olopatadine Hydrochloride in the Treatment of Allergic Conjunctivitis A Real World Comparison of Efficacy and Ocular Comfort  Ganz M, Kolle S, Gausche, Orfan N, Detjen P, Advanced Therapy, 1/1/2003
Should All Asthmatics Undergo Allergen Skin Testing?  Detjen P, J Resp Diseases, 11/1/2002
Atrial Fibrillation Associated with Anaphylaxis During Venom and Pollen Immunology  Patel SC, Detjen PF, Annals of Allergy, Asthma and Immunology, 1/1/2002
A three-Week Comparison of Zaditor and Patanol in the Treatment of Allergic Conjunctivitis  Ganz M, Detjen PF, Kolle S, et al., Ocular Allergies, 1/1/2002
Suppression of Morning Plasma Cortisol Levels in Asthma Patients Receiving Flunisolide vs Fluticasone  Detjen PF, Zoidis J, Johnson R, Philips T, Annals of Allergy, Asthma and Immunology, 1/1/1998
Adrenal Suppression of Plasma and 24-Hour Urinary-Free Cortisol Levels in Patients Receiving Inhaled Fluticasone  Detjen PF, Philips T, Annals of Allergy, Asthma and Immunology, 1/1/1998
Oral Allergy Syndrome or Anaphylaxis?  Detjen PF, Annals of Allergy, Asthma and Immunology, 1/1/1996
Effectiveness of Early Therapy with Corticosteroids in Stevens-Johnson Syndrome: Experience with 41 Cases and a Hypothesis Regarding Pathogenesis  Patterson R, Miller M, Kaplan M, Doan T, Brown J, Detjen PF, et al., Annals of Allergy, 1/1/1994
Idiopathic Anaphylaxis Presenting as Chest Pain  Jacobson MC, Detjen PF, Richmond GW, Annals of Allergy, 1/1/1994
Stinging Insect Allergy and Venom Immunotherapy  Detjen PF, Greenberger PA, Allergy Proceedings, 1/1/1993
Malignant Potentially Fatal Asthma, The Physician’s Dilemma  Detjen PF, Greenberger PA, Grammer LC, Patterson R, Allergy Proceedings, 1/1/1992
Herpes Simplex Virus (HSV) Associated with Recurrent Stevens- Johnson Syndrome: A Management Strategy  Detjen PF, Patterson R, Noskin GA, Phair JP, Loyd SO, Archives of Internal Medicine, 1/1/1992
Stevens-Johnson Syndrome (SJS): Effectiveness of Corticosteroids in Management and Recurrent SJS  Patterson R, Grammer LC, Greenberger PA, Lawrence ID, Zeiss CR, Detjen PF, Ganz MA, Miller TP, Orfan NA, Sonenthal KR, Stoloff R, Allergy Proceedings, 1/1/1992
Platelet Factor 3 Immunoinjury Assay in Sulfamethoxazole-Induced Platelet Lysis  Detjen PF, Shaughnessy NA, Grammer LC, Cohen I, J Allergy Clin Immunol, 1/1/1991

Books/Book Chapters

Corticosteroids in the Management of Allergic Disease. IN: Patterson R (ed), Allergic Diseases: Diagnosis and Management 
Detjen, P
Editors: Patterson, R.J.B. Lippincott Co

Allergic Bronchopulmonary Aspergillosis, IN: Lynch JP (ed), Immunologically Mediated Pulmonary Disease 
Detjen PF, Greenberger PA, Patterson R
Editors: .J.B. Lippincott Co


An Epidemiologic Study of Xolair (omalizumab): Evaluating Clinical Effectiveness and Safety in Pediatric Patients with Moderate to Severe and Difficult to Control Ast… Whyte SA. Detjen PF, Sheridan PH, Malamut KP, Samuelson SH, ACAAI Annual Meeting, Phoenix, 2010

Risk Factors for Adults with a History of Penicillin Allergy Apter, AJ, Wan F, Chittams J, Detjen PF, et al, AAAAI Annual meeting, San Diego, 2007

Treatment of Allergic Conjunctivitis with Ketotifen Fumarate Ophthalmic Solution 0.025%: A Retrospective Analysis in a Clinical Setting Ganz M, Detjen PF, Kolle S, et al, Ocular Allergies, 2002

Comprehensive Asthma Management for Children in Inner City Chicago: A Program Model. Baker L, Detjen PF, Persky V, et al, World Asthma Meeting, Chicago, 2001

Suppression of Morning Plasma Cortisol Levels in Asthma Patients Receiving Flunisolide vs. Fluticasone Detjen PF, Zoidis J, Johnson R, Philips T, Annals of Allergy, Asthma and Immunology, 1998

Adrenal Suppression of Plasma and 24-Hour Urinary-Free Cortisol Levels in Patients Receiving Inhaled Fluticasone Detjen PF, Philips T, Annals of Allergy, Asthma and Immunology, 1998

Idiopathic Anaphylaxis Presenting as Chest Pain Jacobson MC, Detjen PF, Richmond GW, Annals of Allergy Asthma and Immunology, 1994

Platelet Factor 3 Immunoinjury Assay in Sulfamethoxazole-Induced Platelet Lysis Detjen PF, Shaughnessy NA, Grammer LC, Cohen I, J Allergy Clin Immunol, 1991

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