Dr. Eli Silver, MD

Dr. Eli Silver, MD
Dr. Eli Silver is a trusted and dependable allergist and pediatric allergist serving the communities of Mayfield Heights and Westlake, OH. Dr. Silver obtained his medical degree from the Icahn School of Medicine at Mount Sinai. He also completed his internship and residency in pediatrics at Maimonides Medical Center. He further completed his fellowship in pediatric allergy and immunology at St Louis Children’s Hospital.

Dr. Silver is a part of UHMP Allergists. He is board certified by the American Board of Allergy and Immunology and the American Board of Pediatrics. He received research excellence award, academic excellence award, resident of the year award at Maimonides Medical Center, and outstanding teacher award at the Case Western Reserve University School of Medicine.

Patients trust Dr. Silver’s expertise because he consistently provides high quality care that leads to positive and lasting health outcomes. He gives each patient his focused attention, and he prides himself on delivering the best treatment available.

Dr. Silver’s Education and Qualifications:
Medical School – Icahn School of Medicine at Mount Sinai, Doctor of Medicine
Maimonides Medical Center, Internship in Pediatrics
Maimonides Medical Center, Residency in Pediatrics
St. Louis Children’s Hospital, Fellowship in Pediatric Allergy and Immunology
Vanderbilt University (Bachelor’s)

Dr. Silver’s Medical Awards include:
Research Excellence Award, Maimonides Medical Center, 2004
Resident of the Year Award, Maimonides Medical Center, 2004, 2005
Academic Excellence Award, Maimonides Medical Center, 2005
Outstanding Teacher Award, Department of Pediatrics, Case Western Reserve University School of Medicine, 2011
Ranked Top Doctor in Allergy and Immunology in Northeast Ohio, Cleveland Magazine 2015 and 2016

And on ZocDoc, Dr. Silver’s 5 star rating is accompanied by 4 additional awards:
Rapid Registration (you can complete your forms online);
See You Again (patients return to him for ongoing care);
Speedy Response (the office confirms appointments quickly); and
Schedule Hero (his office keeps the schedule running smoothly.)

Liseetsa’s input on Dr. Silver:
Food allergy is Dr. Silver’s passion. He has been following the OIT “story” for over 10 years. As soon as the opportunity to start OIT presented itself, he took it. Among the many OIT protocols he has tried, he feels Dr. Richard Wasserman’s “perfected” protocol to be the “BEST.” So he uses the “Dallas approach” to oral immunotherapy.

During our conversation, Dr. Silver emphasized and empathized with the “daunting” task of keeping children who are allergic to food safe. Fortunately, his own children outgrew their food allergies. So, as you can imagine, he loves his work and sees himself as a partner with his patients and parents on their “road to wellness.”

As we discussed OIT and food allergy discoveries, Dr. Silver expressed a fascination with a study about the ever-changing peanut sensitivity. The study was published in the Journal of Allergy and Clinical Immunology under a long, run-on title: “The eliciting dose of peanut in double-blind, placebo-controlled food challenges decreases with increasing age and specific IgE level in children and young adults”. 

To sum it up:
A food allergy research group from Netherlands was trying to zero-in on the risk factors for severe peanut reactions

They have discovered that an older age, in itself, is a risk factor for more a severe peanut allergy.

In the table below, one can see that it takes a lesser amount of peanut to provoke an allergic reaction among older patients, > 10 y.o. as compared to that among preschoolers, <5 y.o. In other words, it took 10 x fold more peanut protein to cause a reaction in a preschooler as compared to a teenager.

TABLE IV. as you seen, it takes 790 mg of peanut to provoke a reaction in child under 5 y.o as opposed to only 70 mg of peanut to start a reaction in a child older than 10 years.

Also, a higher peanut IgE antibody level was associated with a more severe reaction: “For each increase of 1 kU/L in the peanut-specific antibody IgE level, the risk of reacting to a specific eliciting dose in increased by 1%”, the authors wrote.

In other words, the “perfect storm” of peanut allergy would be a teen with a high peanut antibody level. This is terrible, because for many years we have observed that more severe and deadly peanut reactions tend to happen among teenagers! The common “wisdom” to explain this finding was that the teens are more opt for risk-taking behavior and may not keep the epinephrine handy.

Yet, this Dutch study has discovered that, at least, a part of the explanation is that the very severity of peanut allergy increases with age.

Bottom line, teens are going be teens: we can’t always change their behavior and chain them down to an Epipen, yet, we know that the oral immunotherapy can mitigate this risk and “peanut”-proof our kids. The OIT may even be safer among younger children, as their intrinsic peanut sensitivity has not yet reached its peak.

“Like any study, this report has its limitations, and I am looking forward to see more data published by the Dutch group, but in my mind, it’s a prime time for OIT, now; for peanut sensitivity “does not waste any time”. ~ Eli Silver MD


Dr. Eli Silver
UHMP Allergists

East: 5850 Landerbrook Drive, Suite 100, Mayfield Heights, OH 44124
West: 960 Clague Road, Bldg A, Suite 3280, Westlake, OH 44145
(440) 995-3819

OIT Details

Doctor Name: Dr. Silver
State: Ohio
Allergen: Peanuts, Tree Nuts, Milk, Egg, Wheat, Sesame
Treats single/multi allergens at once: Single
Offers SLIT for food allergens: No

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