Food specific oral immunotherapy: a potential treatment for food allergy. Expert Rev Gastroenterol Hepatol. 2015

Expert Rev Gastroenterol Hepatol. 2015;9(9):1147-59. doi: 10.1586/17474124.2015.1065177. Epub 2015 Jul 9.

Food specific oral immunotherapy: a potential treatment for food allergy.

Abstract

Food allergy is a potentially life-threatening condition affecting up to 8% of children and up to 2% of adults in westernized countries. There are currently no approved treatments for food allergy apart from avoidance. The apparent increase in incidence of food allergies over the past few decades calls attention to the need for effective, disease-modifying therapies for food allergies. Oral immunotherapy (OIT) is a promising experimental treatment in which food allergic patients consume increasing quantities of food in attempt to increase their threshold for allergic reaction. Studies are ongoing to determine whether OIT is capable of safely inducing not only desensitization but also tolerance to the allergenic foods. This article focuses on recent relevant studies of OIT for the treatment of common food allergies.

KEYWORDS:

desensitization; double blind placebo-controlled food challenge; food allergy; omalizumab; oral immunotherapy; probiotic; sustained unresponsiveness; tolerance

LINK TO: Food specific oral immunotherapy: a potential treatment for food allergy. Expert Rev Gastroenterol Hepatol. 2015 Sep;9(9):1147-59.
www.ncbi.nlm.nih.gov/pubmed/26145713

 

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